Our results show that upon TLR4 activation, TUT7, but not TUT4, is upregulated and TUT7 subsequently associates with and oligouridylates to regulate cytokine production. Here we reveal that TLR4 activation induces TUT7, which in turn selectively regulates the production of a subset of cytokines, including Interleukin 6 (IL-6). TUT7 regulates IL-6 expression by controlling ribonuclease … Continue reading Our results show that upon TLR4 activation, TUT7, but not TUT4, is upregulated and TUT7 subsequently associates with and oligouridylates to regulate cytokine production